Taking Nasopharyngeal Carcinoma as an example to explore the regulatory mechanism of long non-coding RNA on Epithelial-Mesenchymal Transition

Abstract

Recently, more studies are actively focusing on NPC and its regulation both at home and abroad. Notably, the quantity of research projects in this field shows an upward trend. However, the specific relationship between NPC and lncRNA only has a few research about its multiple biological factors like genes and signaling pathways. Also, only a limited number of studies are dedicated to this area. This article intends to fill this research gap by systematically searching and analyzing existing research results through literature review and eventually get the whole conclusion. First, the definition of lncRNA and principles of its functioning mechanisms are divided into three patterns. Second, the details regarding oncogenic lncRNA in NPC are given. Third, two core mechanisms of lncRNA are presented with the specific objective of showing the inherent relationship. This article provides theoretical basis and guidance for the treatment of cancer. And particularly offers new insights into and innovative perspectives on the treatment of NPC and other cancers.