A systematic review on high-frequency spinal cord stimulation therapy for neuropathic pain.

Abstract

Neuropathic pain is a complex, chronic pain caused by damage to the nervous system, affecting 6.9% to 10% of the population globally. In contemporary society, the therapeutic efficacy of high-frequency spinal cord stimulation (HF10) at 10 kHz has been confirmed by multiple studies and clinical tests, especially in alleviating pain associated with complex regional pain syndrome (CRPS), diabetes-related neuropathy and Peripheral nerve damage. HF10 therapy not only significantly reduces pain, but also avoids the paresthesia caused by traditional SCS during the treatment process. According to a SENZA study, 88% of participants reported greater than 50% pain reduction after one year, and HF10 excelled at improving daily activities and quality of life. In addition, HF10 treatment has fewer side effects and good long-term effects and is free of paresthesia, making it significantly costeffective. These findings highlight the potential of HF10 as an innovative treatment in the management of chronic neuropathic pain, providing new hope for patients.